| EC |
2.1.1.54 |
| Accepted name: |
deoxycytidylate C-methyltransferase |
| Reaction: |
5,10-methylenetetrahydrofolate + dCMP = dihydrofolate + deoxy-5-methylcytidylate |
| Other name(s): |
deoxycytidylate methyltransferase; dCMP methyltransferase |
| Systematic name: |
5,10-methylenetetrahydrofolate:dCMP C-methyltransferase |
| Comments: |
dCMP is methylated by formaldehyde in the presence of tetrahydrofolate. CMP, dCTP and CTP can act as acceptors, but more slowly. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 61970-01-2 |
| References: |
| 1. |
Kuo, T.-T. and Tu, J. Enzymatic synthesis of deoxy-5-methyl-cytidylic acid replacing deoxycytidylic acid in Xanthomonas oryzae phage Xp12DNA. Nature 263 (1976) 615. [PMID: 980110] |
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| [EC 2.1.1.54 created 1978] |
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