The Enzyme Database

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Accepted name: 25S rRNA (cytosine2278-C5)-methyltransferase
Reaction: S-adenosyl-L-methionine + cytosine2278 in 25S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine2278 in 25S rRNA
Other name(s): RCM1 (gene name)
Systematic name: S-adenosyl-L-methionine:25S rRNA (cytosine2278-C5)-methyltransferase
Comments: The enzyme, found in eukaryotes, is specific for 25S cytosine2278. The numbering corresponds to the enzyme from the yeast Saccharomyces cerevisiae [1].
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Sharma, S., Yang, J., Watzinger, P., Kotter, P. and Entian, K.D. Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively. Nucleic Acids Res. 41 (2013) 9062–9076. [PMID: 23913415]
[EC created 2014]

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