| EC |
2.1.1.311 |
| Accepted name: |
25S rRNA (cytosine2278-C5)-methyltransferase |
| Reaction: |
S-adenosyl-L-methionine + cytosine2278 in 25S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine2278 in 25S rRNA |
| Other name(s): |
RCM1 (gene name) |
| Systematic name: |
S-adenosyl-L-methionine:25S rRNA (cytosine2278-C5)-methyltransferase |
| Comments: |
The enzyme, found in eukaryotes, is specific for 25S cytosine2278. The numbering corresponds to the enzyme from the yeast Saccharomyces cerevisiae [1]. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Sharma, S., Yang, J., Watzinger, P., Kotter, P. and Entian, K.D. Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively. Nucleic Acids Res. 41 (2013) 9062–9076. [DOI] [PMID: 23913415] |
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| [EC 2.1.1.311 created 2014] |
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