| EC |
2.1.1.309 |
| Accepted name: |
18S rRNA (guanine1575-N7)-methyltransferase |
| Reaction: |
S-adenosyl-L-methionine + guanine1575 in 18S rRNA = S-adenosyl-L-homocysteine + N7-methylguanine1575 in 18S rRNA |
| Other name(s): |
18S rRNA methylase Bud23; BUD23 (gene name) |
| Systematic name: |
S-adenosyl-L-methionine:18S rRNA (guanine1575-N7)-methyltransferase |
| Comments: |
The enzyme, found in eukaryotes, is involved in pre-rRNA processing. The numbering corresponds to the enzyme from the yeast Saccharomyces cerevisiae [1]. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
White, J., Li, Z., Sardana, R., Bujnicki, J.M., Marcotte, E.M. and Johnson, A.W. Bud23 methylates G1575 of 18S rRNA and is required for efficient nuclear export of pre-40S subunits. Mol. Cell Biol. 28 (2008) 3151–3161. [DOI] [PMID: 18332120] |
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| [EC 2.1.1.309 created 2014] |
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