The Enzyme Database

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EC 2.1.1.309     
Accepted name: 18S rRNA (guanine1575-N7)-methyltransferase
Reaction: S-adenosyl-L-methionine + guanine1575 in 18S rRNA = S-adenosyl-L-homocysteine + N7-methylguanine1575 in 18S rRNA
Other name(s): 18S rRNA methylase Bud23; BUD23 (gene name)
Systematic name: S-adenosyl-L-methionine:18S rRNA (guanine1575-N7)-methyltransferase
Comments: The enzyme, found in eukaryotes, is involved in pre-rRNA processing. The numbering corresponds to the enzyme from the yeast Saccharomyces cerevisiae [1].
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  White, J., Li, Z., Sardana, R., Bujnicki, J.M., Marcotte, E.M. and Johnson, A.W. Bud23 methylates G1575 of 18S rRNA and is required for efficient nuclear export of pre-40S subunits. Mol. Cell Biol. 28 (2008) 3151–3161. [PMID: 18332120]
[EC 2.1.1.309 created 2014]
 
 


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