| EC |
2.1.1.287 |
| Accepted name: |
25S rRNA (adenine645-N1)-methyltransferase |
| Reaction: |
S-adenosyl-L-methionine + adenine645 in 25S rRNA = S-adenosyl-L-homocysteine + N1-methyladenine645 in 25S rRNA |
| Other name(s): |
25S rRNA m1A645 methyltransferase; Rrp8 |
| Systematic name: |
S-adenosyl-L-methionine:25S rRNA (adenine645-N1)-methyltransferase |
| Comments: |
The enzyme is found in eukaryotes. The adenine position refers to rRNA in the yeast Saccharomyces cerevisiae, in which the enzyme is important for ribosome biogenesis. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Peifer, C., Sharma, S., Watzinger, P., Lamberth, S., Kotter, P. and Entian, K.D. Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA. Nucleic Acids Res. 41 (2013) 1151–1163. [DOI] [PMID: 23180764] |
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| [EC 2.1.1.287 created 2013] |
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