| EC |
2.1.1.252 |
| Accepted name: |
tetramethylammonium—corrinoid protein Co-methyltransferase |
| Reaction: |
tetramethylammonium + a [Co(I) tetramethylammonium-specific corrinoid protein] = a [methyl-Co(III) tetramethylammonium-specific corrinoid protein] + trimethylamine |
| Other name(s): |
mtqB (gene name); tetramethylammonium methyltransferase |
| Systematic name: |
tetramethylammonium:5-hydroxybenzimidazolylcobamide Co-methyltransferase |
| Comments: |
The enzyme, which catalyses the transfer of a methyl group from tetramethylammonium to a tetramethylammonium-specific corrinoid protein (MtqC), is involved in methanogenesis from tetramethylammonium. Methylation of the corrinoid protein requires the central cobalt to be in the Co(I) state. During methylation the cobalt is oxidized to the Co(III) state. The methylated corrinoid protein is substrate for EC 2.1.1.253, methylated tetramethylammonium-specific corrinoid protein:coenzyme M methyltransferase. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Asakawa, S., Sauer, K., Liesack, W. and Thauer, R.K. Tetramethylammonium:coenzyme M methyltransferase system from methanococcoides s. Arch. Microbiol. 170 (1998) 220–226. [PMID: 9732435] |
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| [EC 2.1.1.252 created 2012] |
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