In contrast to the archaeal enzyme tRNA (guanine10-N2)-dimethyltransferase (EC 126.96.36.199), tRNA (guanine10-N2)-methyltransferase from yeast does not catalyse the methylation from N2-methylguanine10 to N2-dimethylguanine10 in tRNA.
Purushothaman, S.K., Bujnicki, J.M., Grosjean, H. and Lapeyre, B. Trm11p and Trm112p are both required for the formation of 2-methylguanosine at position 10 in yeast tRNA. Mol. Cell Biol.25 (2005) 4359–4370. [DOI] [PMID: 15899842]
[EC 188.8.131.52 created 2011 (EC 184.108.40.206 created 1972, part transferred 2011 to EC 220.127.116.11)]