The Enzyme Database

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Accepted name: tRNASer (uridine44-2′-O)-methyltransferase
Reaction: S-adenosyl-L-methionine + uridine44 in tRNASer = S-adenosyl-L-homocysteine + 2′-O-methyluridine44 in tRNASer
Other name(s): TRM44
Systematic name: S-adenosyl-L-methionine:tRNASer (uridine44-2′-O)-methyltransferase
Comments: The 2′-O-methylation of uridine44 contributes to stability of tRNASer(CGA).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Kotelawala, L., Grayhack, E.J. and Phizicky, E.M. Identification of yeast tRNA Um44 2′-O-methyltransferase (Trm44) and demonstration of a Trm44 role in sustaining levels of specific tRNASer species. RNA 14 (2008) 158–169. [PMID: 18025252]
[EC created 2011]

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