| EC |
2.1.1.191 |
| Accepted name: |
23S rRNA (cytosine1962-C5)-methyltransferase |
| Reaction: |
S-adenosyl-L-methionine + cytosine1962 in 23S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine1962 in 23S rRNA |
| Other name(s): |
RlmI; rRNA large subunit methyltransferase I; YccW |
| Systematic name: |
S-adenosyl-L-methionine:23S rRNA (cytosine1962-C5)-methyltransferase |
| Comments: |
The enzyme specifically methylates cytosine1962 at C5 in 23S rRNA. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Purta, E., O'Connor, M., Bujnicki, J.M. and Douthwaite, S. YccW is the m5C methyltransferase specific for 23S rRNA nucleotide 1962. J. Mol. Biol. 383 (2008) 641–651. [DOI] [PMID: 18786544] |
| 2. |
Sunita, S., Tkaczuk, K.L., Purta, E., Kasprzak, J.M., Douthwaite, S., Bujnicki, J.M. and Sivaraman, J. Crystal structure of the Escherichia coli 23S rRNA:m5C methyltransferase RlmI (YccW) reveals evolutionary links between RNA modification enzymes. J. Mol. Biol. 383 (2008) 652–666. [DOI] [PMID: 18789337] |
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| [EC 2.1.1.191 created 2010] |
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