| EC |
2.1.1.170 |
| Accepted name: |
16S rRNA (guanine527-N7)-methyltransferase |
| Reaction: |
S-adenosyl-L-methionine + guanine527 in 16S rRNA = S-adenosyl-L-homocysteine + N7-methylguanine527 in 16S rRNA |
| Other name(s): |
ribosomal RNA small subunit methyltransferase G; 16S rRNA methyltransferase RsmG; GidB; rsmG (gene name) |
| Systematic name: |
S-adenosyl-L-methionine:16S rRNA (guanine527-N7)-methyltransferase |
| Comments: |
The enzyme specifically methylates guanine527 at N7 in 16S rRNA. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Okamoto, S., Tamaru, A., Nakajima, C., Nishimura, K., Tanaka, Y., Tokuyama, S., Suzuki, Y. and Ochi, K. Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria. Mol. Microbiol. 63 (2007) 1096–1106. [DOI] [PMID: 17238915] |
| 2. |
Romanowski, M.J., Bonanno, J.B. and Burley, S.K. Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold. Proteins 47 (2002) 563–567. [DOI] [PMID: 12001236] |
|
| [EC 2.1.1.170 created 2010] |
| |
|
| |
|
Printable version