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Accepted name: columbamine
S-adenosyl- L-methionine + columbamine = S-adenosyl- L-homocysteine + palmatine
For diagram of columbamine, palmatine and corydaline biosynthesis,
S-adenosyl- L-methionine:columbamine O-methyltransferase
Comments: The product of this reaction is a protoberberine alkaloid that is widely distributed in the plant kingdom. This enzyme is distinct in specificity from
EC 220.127.116.11, 8-hydroxyquercetin 8- O-methyltransferase.
Links to other databases:
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 105843-76-3
Rueffer, M., Amann, M., Zenk, M.H. S-Adenosyl-
L-methionine:columbamine O-methyltransferase, a compartmentalized enzyme in protoberberine biosynthesis. Plant Cell Reports 3 (1986) 182–185.
[EC 18.104.22.168 created 1999]
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