| EC |
2.1.1.116 |
| Accepted name: |
3′-hydroxy-N-methyl-(S)-coclaurine 4′-O-methyltransferase |
| Reaction: |
S-adenosyl-L-methionine + 3′-hydroxy-N-methyl-(S)-coclaurine = S-adenosyl-L-homocysteine + (S)-reticuline |
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For diagram of reticuline biosynthesis, click here |
| Systematic name: |
S-adenosyl-L-methionine:3′-hydroxy-N-methyl-(S)-coclaurine 4′-O-methyltransferase |
| Comments: |
Involved in isoquinoline alkaloid metabolism in plants. The enzyme has also been shown to catalyse the methylation of (RS)-laudanosoline, (S)-3′-hydroxycoclaurine and (RS)-7-O-methylnorlaudanosoline. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 132084-81-2 |
| References: |
| 1. |
Frenzel, T., Zenk, M.H. S-Adenosyl-L-methionine: 3′-hydroxy-N-methyl-(S)-coclaurine 4′-O-methyltransferase, a regio- and stereoselective enzyme of the (S)-reticuline pathway. Phytochemistry 29 (1990) 3505–3511. [DOI] |
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| [EC 2.1.1.116 created 1999] |
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