This is a large group of enzymes, most of which, with enzymes of similar site specificity listed as EC 220.127.116.11 (type 1 site-specific deoxyribonuclease), EC 18.104.22.168 (type II site-specific deoxyribonuclease) or EC 22.214.171.124 (type III site-specific deoxyribonuclease), form so-called ’restriction-modification systems’. A complete listing of all of these enzymes has been produced by R.J. Roberts and is available on-line at http://rebase.neb.com/rebase/rebase.html.
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