This is a large group of enzymes, most of which, with enzymes of similar site specificity listed as EC 184.108.40.206 (type 1 site-specific deoxyribonuclease), EC 220.127.116.11 (type II site-specific deoxyribonuclease) or EC 18.104.22.168 (type III site-specific deoxyribonuclease), form so-called ’restriction-modification systems’. A complete listing of all of these enzymes has been produced by R.J. Roberts and is available on-line at http://rebase.neb.com/rebase/rebase.html.
Kessler, C. and Manta, V. Specificity of restriction endonucleases and DNA modification methyltransferases: a review. Gene92 (1990) 1–248. [DOI] [PMID: 2172084]
Klimasauskas, S., Timinskas, A., Menkevicius, S., Butkiene, D., Butkus, V. and Janulaitis, A. Sequence motifs characteristic of DNA[cytosine-N4]methyltransferases: similarity to adenine and cytosine-C5 DNA-methylases. Nucleic Acids Res.17 (1989) 9823–9832. [DOI] [PMID: 2690010]
Roberts, R.J. Restriction enzymes and their isoschizomers. Nucleic Acids Res.18 (1990) 2331–2365. [PMID: 2159140]
Yuan, R. Structure and mechanism of multifunctional restriction endonucleases. Annu. Rev. Biochem.50 (1981) 285–319. [DOI] [PMID: 6267988]