ExplorEnz: EC 1.5.1.32

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1.5.1.32

Accepted name:

vomilenine reductase

Reaction:

1,2-dihydrovomilenine + NADP⁺ = vomilenine + NADPH + H⁺

For diagram of ajmaline, vinorine, vomilenine and raucaffricine biosynthesis, click here

Systematic name:

1,2-dihydrovomilenine:NADP⁺ oxidoreductase

Comments:

Forms part of the ajmaline biosynthesis pathway.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 462127-03-3

References:

1.	von Schumann, G., Gao, S. and Stöckigt, J. Vomilenine reductase - a novel enzyme catalyzing a crucial step in the biosynthesis of the therapeutically applied antiarrhythmic alkaloid ajmaline. J. Bioorg. Med. Chem. 10 (2002) 1913–1918. [DOI] [PMID: 11937349]

[EC 1.5.1.32 created 2002]