The Enzyme Database

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EC 1.5.1.32     
Accepted name: vomilenine reductase
Reaction: 1,2-dihydrovomilenine + NADP+ = vomilenine + NADPH + H+
For diagram of ajmaline, vinorine, vomilenine and raucaffricine biosynthesis, click here
Systematic name: 1,2-dihydrovomilenine:NADP+ oxidoreductase
Comments: Forms part of the ajmaline biosynthesis pathway.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 462127-03-3
References:
1.  von Schumann, G., Gao, S. and Stöckigt, J. Vomilenine reductase - a novel enzyme catalyzing a crucial step in the biosynthesis of the therapeutically applied antiarrhythmic alkaloid ajmaline. J. Bioorg. Med. Chem. 10 (2002) 1913–1918. [PMID: 11937349]
[EC 1.5.1.32 created 2002]
 
 


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