| EC |
1.5.1.25 |
| Accepted name: |
thiomorpholine-carboxylate dehydrogenase |
| Reaction: |
thiomorpholine 3-carboxylate + NAD(P)+ = 3,4-dehydro-thiomorpholine-3-carboxylate + NAD(P)H + H+ |
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For diagram of reaction, click here |
| Other name(s): |
ketimine reductase; ketimine-reducing enzyme |
| Systematic name: |
thiomorpholine-3-carboxylate:NAD(P)+ 5,6-oxidoreductase |
| Comments: |
The product is the cyclic imine of the 2-oxoacid corresponding to S-(2-aminoethyl)cysteine. In the reverse direction, a number of other cyclic unsaturated compounds can act as substrates, but more slowly. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 115232-54-7 |
| References: |
| 1. |
Nardini, M., Ricci, G., Caccuri, A.M., Solinas, S.P., Vesci, L. and Cavallini, D. Purification and characterization of a ketimine-reducing enzyme. Eur. J. Biochem. 173 (1988) 689–694. [DOI] [PMID: 3371353] |
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| [EC 1.5.1.25 created 1990] |
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