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Accepted name: thiomorpholine-carboxylate dehydrogenase
Reaction: thiomorpholine 3-carboxylate + NAD(P)
= 3,4-dehydro-thiomorpholine-3-carboxylate + NAD(P)H + H + +
For diagram of reaction,
Other name(s): ketimine reductase; ketimine-reducing enzyme
Systematic name: thiomorpholine-3-carboxylate:NAD(P)
Comments: The product is the cyclic imine of the 2-oxoacid corresponding to
S-(2-aminoethyl)cysteine. In the reverse direction, a number of other cyclic unsaturated compounds can act as substrates, but more slowly.
Links to other databases:
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 115232-54-7
Nardini, M., Ricci, G., Caccuri, A.M., Solinas, S.P., Vesci, L. and Cavallini, D. Purification and characterization of a ketimine-reducing enzyme.
Eur. J. Biochem. 173 (1988) 689–694. [PMID: 3371353]
[EC 22.214.171.124 created 1990]
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