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Accepted name: 2-methylacyl-CoA dehydrogenase
Reaction: 2-methylbutanoyl-CoA + acceptor = 2-methylbut-2-enoyl-CoA + reduced acceptor
Other name(s): branched-chain acyl-CoA dehydrogenase; 2-methyl branched chain acyl-CoA dehydrogenase; 2-methylbutanoyl-CoA:(acceptor) oxidoreductase
Systematic name: 2-methylbutanoyl-CoA:acceptor oxidoreductase
Comments: Also oxidizes 2-methylpropanoyl-CoA. Not identical with
EC 220.127.116.11 (butyryl-CoA dehydrogenase), EC 18.104.22.168 (medium-chain acyl-CoA dehydrogenase), EC 22.214.171.124 (long-chain acyl-CoA dehydrogenase), EC 126.96.36.199 (very-long-chain acyl-CoA dehydrogenase) or EC 188.8.131.52 (isovaleryl-CoA dehydrogenase).
Links to other databases:
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 85130-32-1
Ikeda, Y., Dabrowski, C. and Tanaka, K. Separation and properties of five distinct acyl-CoA dehydrogenases from rat liver mitochondria. Identification of a new 2-methyl branched chain acyl-CoA dehydrogenase.
J. Biol. Chem. 258 (1983) 1066–1076. [PMID: 6401712]
[EC 184.108.40.206 created 1986]
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