| EC |
1.3.1.71 |
| Accepted name: |
Δ24(241)-sterol reductase |
| Reaction: |
ergosterol + NADP+ = ergosta-5,7,22,24(241)-tetraen-3β-ol + NADPH + H+ |
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For diagram of sterol-sidechain modification, click here |
| Other name(s): |
sterol Δ24(28)-methylene reductase; sterol Δ24(28)-reductase |
| Systematic name: |
ergosterol:NADP+ Δ24(241)-oxidoreductase |
| Comments: |
Acts on a range of steroids with a 24(241)-double bond. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Neal, W.D. and Parks, L.W. Sterol 24(28) methylene reductase in Saccharomyces cerevisiae. J. Bacteriol. 129 (1977) 1375–1378. [PMID: 14922] |
| 2. |
Zweytick, D., Hrastnik, C. , Kohlwein. S.D. and Daum, G. Biochemical characterization and subcellular localization of the sterol C-24(28) reductase, erg4p, from the yeast Saccharomyces cerevisiae. FEBS Lett. 470 (2000) 83–87. [DOI] [PMID: 10722850] |
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| [EC 1.3.1.71 created 2001, modified 2002] |
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