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Your query returned 1 entry. Printable version
EC | 1.3.1.124 | ||||||||||||
Accepted name: | 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] | ||||||||||||
Reaction: | (1) a (3E)-3-enoyl-CoA + NADP+ = a (2E,4E)-2,4-dienoyl-CoA + NADPH + H+ (2) a (3E)-3-enoyl-CoA + NADP+ = a (2E,4Z)-2,4-dienoyl-CoA + NADPH + H+ |
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Other name(s): | SPS19 (gene name); DECR1 (gene name); DECR2 (gene name); Δ2,Δ4-dienoyl-CoA reductase (ambiguous) | ||||||||||||
Systematic name: | (3E)-3-enoyl-CoA:NADP+ 4-oxidoreductase | ||||||||||||
Comments: | This enzyme, characterized from eukaryotic organisms, catalyses the reduction of either (2E,4E)-2,4-dienoyl-CoA or (2E,4Z)-2,4-dienoyl-CoA to (3E)-3-enoyl-CoA. The best substrates for the enzyme from bovine liver have a chain-length of 8 or 10 carbons. Mammals possess both mitochondrial and peroxisomal variants of this enzyme. cf. EC 1.3.1.34, 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]. | ||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||||||
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