The Enzyme Database

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EC 1.21.3.5     
Accepted name: sulochrin oxidase [(-)-bisdechlorogeodin-forming]
Reaction: 2 sulochrin + O2 = 2 (-)-bisdechlorogeodin + 2 H2O
For diagram of reaction, click here
Other name(s): sulochrin oxidase
Systematic name: sulochrin:oxygen oxidoreductase (cyclizing, (-)-specific)
Comments: Also acts on several diphenols and phenylenediamines, but has low affinity for these substrates. Involved in the biosynthesis of mould metabolites related to the antibiotic griseofulvin.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 82469-87-2
References:
1.  Nordlöv, H. and Gatenbeck, S. Enzymatic synthesis of (+)- and (-)-bisdechlorogeodin with sulochrin oxidase from Penicillium frequentans and Oospora sulphurea ochracea. Arch. Microbiol. 131 (1982) 208–211. [PMID: 7049104]
[EC 1.21.3.5 created 1986 as EC 1.10.3.8, transferred 2002 to EC 1.21.3.5]
 
 


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