The Enzyme Database

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EC 1.21.1.2     
Accepted name: 2,4-dichlorobenzoyl-CoA reductase
Reaction: 4-chlorobenzoyl-CoA + NADP+ + chloride = 2,4-dichlorobenzoyl-CoA + NADPH + H+
Systematic name: 4-chlorobenzoyl-CoA:NADP+ oxidoreductase (halogenating)
Comments: The enzyme, characterized from Corynebacterium strains able to grow on 2,4-dichlorobenzoate, forms part of the 2,4-dichlorobenzoate degradation pathway.
Links to other databases: BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc
References:
1.  Romanov, V. and Hausinger, R.P. NADPH-dependent reductive ortho dehalogenation of 2,4-dichlorobenzoic acid in Corynebacterium sepedonicum KZ-4 and Coryneform bacterium strain NTB-1 via 2,4-dichlorobenzoyl coenzyme A. J. Bacteriol. 178 (1996) 2656–2661. [DOI] [PMID: 8626335]
[EC 1.21.1.2 created 2000 as EC 1.3.1.63, modified 2011, transferred 2015 to EC 1.21.1.2]
 
 


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