Reduction of arsenate is part of a defense mechanism of the cell against toxic arsenate. The substrate arseno-mycothiol is formed by EC 22.214.171.124 (arsenate:mycothiol transferase). A second mycothiol recycles mycoredoxin and forms mycothione.
Ordonez, E., Van Belle, K., Roos, G., De Galan, S., Letek, M., Gil, J.A., Wyns, L., Mateos, L.M. and Messens, J. Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange. J. Biol. Chem.284 (2009) 15107–15116. [PMID: 19286650]