EC |
1.2.3.6 |
Accepted name: |
pyruvate oxidase (CoA-acetylating) |
Reaction: |
pyruvate + CoA + O2 = acetyl-CoA + CO2 + H2O2 |
Systematic name: |
pyruvate:oxygen 2-oxidoreductase (CoA-acetylating) |
Comments: |
A flavoprotein (FAD). May be identical with EC 1.2.7.1 pyruvate synthase. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 62213-57-4 |
References: |
1. |
Reeves, R.E., Warren, L.G., Susskind, B. and Lo, H.-S. An energy-conserving pyruvate-to-acetate pathway in Entamoeba histolytica. Pyruvate synthase and a new acetate thiokinase. J. Biol. Chem. 252 (1977) 726–731. [PMID: 13076] |
2. |
Takeuchi, T., Weinbach, E.C. and Diamond, L.S. Pyruvate oxidase (CoA acetylating) in Entamoeba histolytica. Biochem. Biophys. Res. Commun. 65 (1975) 591–596. [DOI] [PMID: 167776] |
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[EC 1.2.3.6 created 1976] |
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