EC |
1.2.1.98 |
Accepted name: |
2-hydroxy-2-methylpropanal dehydrogenase |
Reaction: |
2-hydroxy-2-methylpropanal + NAD+ + H2O = 2-hydroxy-2-methylpropanoate + NADH + H+ |
Other name(s): |
mpdC (gene name) |
Systematic name: |
2-hydroxy-2-methylpropanal:NAD+ oxidoreductase |
Comments: |
This bacterial enzyme is involved in the degradation pathways of the alkene 2-methylpropene and the fuel additive tert-butyl methyl ether (MTBE), a widely occurring groundwater contaminant. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Lopes Ferreira, N., Labbe, D., Monot, F., Fayolle-Guichard, F. and Greer, C.W. Genes involved in the methyl tert-butyl ether (MTBE) metabolic pathway of Mycobacterium austroafricanum IFP 2012. Microbiology 152 (2006) 1361–1374. [DOI] [PMID: 16622053] |
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[EC 1.2.1.98 created 2016] |
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