| EC |
1.17.5.2 |
| Accepted name: |
caffeine dehydrogenase |
| Reaction: |
caffeine + ubiquinone + H2O = 1,3,7-trimethylurate + ubiquinol |
| Glossary: |
caffeine = 1,3,7-trimethylxanthine |
| Systematic name: |
caffeine:ubiquinone oxidoreductase |
| Comments: |
This enzyme, characterized from the soil bacterium Pseudomonas sp. CBB1, catalyses the incorporation of an oxygen atom originating from a water molecule into position C-8 of caffeine. It can also use theobromine as substrate. The enzyme utilizes short-tail ubiquinones as the preferred electron acceptor. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Yu, C.L., Kale, Y., Gopishetty, S., Louie, T.M. and Subramanian, M. A novel caffeine dehydrogenase in Pseudomonas sp. strain CBB1 oxidizes caffeine to trimethyluric acid. J. Bacteriol. 190 (2008) 772–776. [DOI] [PMID: 17981969] |
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| [EC 1.17.5.2 created 2010] |
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