ExplorEnz: EC 1.17.3.5

1.17.3.5

Accepted name:

4-oxocyclohexanecarboxylate 2-dehydrogenase

Reaction:

4-oxocyclohexane-1-carboxylate + O₂ = 4-oxocyclohex-2-ene-1-carboxylate + H₂O₂

Glossary:

4-oxocyclohexane-1-carboxylate = 4-oxocyclohexanecarboxylate

Other name(s):

chcC1 (gene name); 4-oxocyclohexanecarboxylate desaturase I; 4-oxocyclohexanecarboxylate 2-desaturase

Systematic name:

4-oxocyclohexane-1-carboxylate:oxygen oxidoreductase (4-oxocyclohex-2-ene-1-carboxylate-forming)

Comments:

Contains FAD. The enzyme, characterized from the bacterium Corynebacterium cyclohexanicum, participates in a cyclohexane-1-carboxylate degradation pathway.

References:

1.	Kaneda, T., Obata, H. and Tokumoto, M. Aromatization of 4-oxocyclohexanecarboxylic acid to 4-hydroxybenzoic acid by two distinctive desaturases from Corynebacterium cyclohexanicum. Properties of two desaturases. Eur. J. Biochem. 218 (1993) 997–1003. [PMID: 8281951]
2.	Yamamoto, T., Hasegawa, Y., Lau, P.CK. and Iwaki, H. Identification and characterization of a chc gene cluster responsible for the aromatization pathway of cyclohexanecarboxylate degradation in Sinomonas cyclohexanicum ATCC 51369. J. Biosci. Bioeng. 132 (2021) 621–629. [PMID: 34583900]

[EC 1.17.3.5 created 2024]