|
|
Your query returned 1 entry. 
Printable version
| EC | 1.14.19.71 | ||
| Accepted name: | fumitremorgin C synthase | ||
| Reaction: | tryprostatin A + [reduced NADPH—hemoprotein reductase] + O2 = fumitremorgin C + [oxidized NADPH—hemoprotein reductase] + 2 H2O | ||
| For diagram of fumitremorgin alkaloid biosynthesis (part 1), click here | |||
| Glossary: | tryprostatin A = (3S,8aS)-3-{[6-methoxy-2-(3-methylbut-2-en-1-yl)-1H-indol-3-yl]methyl}hexahydropyrrolo[1,2-a]pyrazine-1,4-dione fumitremorgin C = (5aS,12S,14aS)-9-methoxy-12-(2-methylprop-1-en-1-yl)-1,2,3,5a,6,11,12,14a-octahydro-5H,14H-pyrrolo[1′′,2′′:4′,5′]pyrazino[1′,2′:1,6]pyrido[3,4-b]indole-5,14-dione |
||
| Other name(s): | ftmE (gene name) | ||
| Systematic name: | tryprostatin A,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase | ||
| Comments: | A cytochrome P-450 (heme-thiolate) protein. The protein from the fungus Aspergillus fumigatus also has activity with tryprostatin B forming demethoxyfumitremorgin C. Involved in the biosynthetic pathways of several indole alkaloids such as fumitremorgins and verruculogen. | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
| References: |
| ||