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Your query returned 1 entry. 
Printable version
| EC | 1.14.19.50 | ||
| Accepted name: | noroxomaritidine synthase | ||
| Reaction: | (1) 4′-O-methylnorbelladine + [reduced NADPH—hemoprotein reductase] + O2 = (4aR,10bS)-noroxomaritidine + [oxidized NADPH—hemoprotein reductase] + 2 H2O (2) 4′-O-methylnorbelladine + [reduced NADPH—hemoprotein reductase] + O2 = (4aS,10bR)-noroxomaritidine + [oxidized NADPH—hemoprotein reductase] + 2 H2O |
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| For diagram of noroxomaritidine biosynthesis, click here | |||
| Glossary: | 4′-O-methylnorbelladine = 5-({[2-(4-hydroxyphenyl)ethyl]amino}methyl)-2-methoxyphenol noroxomaritidine = 8-hydroxy-9-methoxy-4,4a-dihydro-3H,6H-5,10b-ethanophenanthridin-3-one |
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| Other name(s): | CYP96T1 (gene name) | ||
| Systematic name: | 4′-O-methylnorbelladine,NADPH—hemoprotein reductase:oxygen oxidoreductase (noroxomaritidine-forming) | ||
| Comments: | A P-450 (heme-thiolate) enzyme. The enzyme, characterized from Narcissus pseudonarcissus (daffodil), forms the two enantiomers of the Amaryllidacea alkaloid noroxomaritidine by catalysing intramolecular oxidative para-para′ phenol coupling. The oxidation involves molecular oxygen without its incorporation into the product. | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
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