The enzyme, characterized from Pseudomonas spp., is involved in a dimethyl sulfide degradation pathway. It is dependent on NAD(P)H-dependent FMN reductase (EC 18.104.22.168, EC 22.214.171.124, or EC 126.96.36.199), which provides it with reduced FMN. The product, methanesulfinate, is oxidized spontaneously to methanesulfonate in the presence of dioxygen and FMNH2.
Endoh, T., Habe, H., Nojiri, H., Yamane, H. and Omori, T. The σ54-dependent transcriptional activator SfnR regulates the expression of the Pseudomonas putidasfnFG operon responsible for dimethyl sulphone utilization. Mol. Microbiol.55 (2005) 897–911. [DOI] [PMID: 15661012]
Wicht, D.K. The reduced flavin-dependent monooxygenase SfnG converts dimethylsulfone to methanesulfinate. Arch. Biochem. Biophys.604 (2016) 159–166. [DOI] [PMID: 27392454]