The Enzyme Database

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Accepted name: tabersonine 16-hydroxylase
Reaction: tabersonine + NADPH + H+ + O2 = 16-hydroxytabersonine + NADP+ + H2O
For diagram of vindoline biosynthesis, click here
Other name(s): tabersonine-11-hydroxylase; T11H
Systematic name: tabersonine,NADPH:oxygen oxidoreductase (16-hydroxylating)
Comments: A heme-thiolate protein (P-450).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 250378-34-8
1.  St-Pierre, B. and De Luca, V. A cytochrome-P-450 monooxygenase catalyzes the first step in the conversion of tabersonine to vindoline in Catharanthus-roseus. Plant Physiol. 109 (1995) 131–139. [PMID: 12228585]
[EC created 2002]

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