The Enzyme Database

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Accepted name: flavonoid 3′-monooxygenase
Reaction: a flavonoid + NADPH + H+ + O2 = a 3′-hydroxyflavonoid + NADP+ + H2O
For diagram of flavonoid biosynthesis, click here and for diagram of the biosynthesis of naringenin derivatives, click here
Other name(s): flavonoid 3′-hydroxylase; flavonoid 3-hydroxylase (erroneous); NADPH:flavonoid-3′-hydroxylase; flavonoid 3-monooxygenase (erroneous)
Systematic name: flavonoid,NADPH:oxygen oxidoreductase (3′-hydroxylating)
Comments: Acts on a number of flavonoids, including naringenin and dihydrokaempferol. Does not act on 4-coumarate or 4-coumaroyl-CoA.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 75991-44-5
1.  Forkmann, G., Heller, W. and Grisebach, H. Anthocyanin biosynthesis in flowers of Matthiola incana flavanone 3- and flavonoid 3′-hydroxylases. Z. Naturforsch. C: Biosci. 35 (1980) 691–695.
[EC created 1983]

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