The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

Accepted name: ent-sandaracopimaradiene 3-hydroxylase
Reaction: ent-sandaracopimaradiene + NADPH + H+ + O2 = ent-sandaracopimaradien-3β-ol + NADP+ + H2O
For diagram of oryzalexins biosynthesis, click here
Glossary: ent-sandaracopimaradiene = ent-13α-pimara-8(14),15-diene = (4aR,4bR,7S,10aR)-7-ethenyl-1,1,4a,7-tetramethyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydrophenanthrene
Other name(s): CYP701A; OsKOL4
Systematic name: ent-sandaracopimaradiene,NADPH:oxygen oxidoreductase (ent-sandaracopimaradien-3β-ol forming)
Comments: A heme-thiolate protein (cytochrome P-450). Isolated from Oryza sativa (rice). Participates in the pathway for the biosynthesis of oryzalexins, a group of related phytoalexins produced by rice.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Wang, Q., Hillwig, M.L., Wu, Y. and Peters, R.J. CYP701A8: a rice ent-kaurene oxidase paralog diverted to more specialized diterpenoid metabolism. Plant Physiol. 158 (2012) 1418–1425. [PMID: 22247270]
2.  Wu, Y., Wang, Q., Hillwig, M.L. and Peters, R.J. Picking sides: distinct roles for CYP76M6 and CYP76M8 in rice oryzalexin biosynthesis. Biochem. J. 454 (2013) 209–216. [PMID: 23795884]
[EC created 2014]

Data © 2001–2018 IUBMB
Web site © 2005–2018 Andrew McDonald