| EC |
1.14.12.7 |
| Accepted name: |
phthalate 4,5-dioxygenase |
| Reaction: |
phthalate + NADH + H+ + O2 = cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ |
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For diagram of reaction, click here |
| Other name(s): |
PDO ; phthalate dioxygenase |
| Systematic name: |
phthalate,NADH:oxygen oxidoreductase (4,5-hydroxylating) |
| Comments: |
A system, containing a reductase which is an iron-sulfur flavoprotein (FMN), an iron-sulfur oxygenase, and no independent ferredoxin. Requires Fe2+. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 63626-44-8 |
| References: |
| 1. |
Batie, C.J., LaHaie, E. and Ballou, D.P. Purification and characterization of phthalate oxygenase and phthalate oxygenase reductase from Pseudomonas cepacia. J. Biol. Chem. 262 (1987) 1510–1518. [PMID: 3805038] |
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| [EC 1.14.12.7 created 1990] |
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