The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

EC 1.14.12.4     
Accepted name: 3-hydroxy-2-methylpyridinecarboxylate dioxygenase
Reaction: 3-hydroxy-2-methylpyridine-5-carboxylate + NAD(P)H + H+ + O2 = 2-(acetamidomethylene)succinate + NAD(P)+
Other name(s): methylhydroxypyridinecarboxylate oxidase; 2-methyl-3-hydroxypyridine 5-carboxylic acid dioxygenase; methylhydroxypyridine carboxylate dioxygenase; 3-hydroxy-3-methylpyridinecarboxylate dioxygenase [incorrect]; 3-hydroxy-2-methylpyridine-5-carboxylate,NAD(P)H:oxygen oxidoreductase (decyclizing)
Systematic name: 3-hydroxy-2-methylpyridine-5-carboxylate,NAD(P)H:oxygen oxidoreductase (ring-opening)
Comments: A flavoprotein (FAD).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, UM-BBD, CAS registry number: 37256-69-2
References:
1.  Sparrow, L.G., Ho, P.P.K., Sundaram, T.K., Zach, D., Nyns, E.J. and Snell, E.E. The bacterial oxidation of vitamin B6. VII. Purification, properties, and mechanism of action of an oxygenase which cleaves the 3-hydroxypyridine ring. J. Biol. Chem. 244 (1969) 2590–2600. [PMID: 4306031]
[EC 1.14.12.4 created 1972]
 
 


Data © 2001–2016 IUBMB
Web site © 2005–2016 Andrew McDonald