The Enzyme Database

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EC 1.14.11.10     
Accepted name: pyrimidine-deoxynucleoside 1′-dioxygenase
Reaction: 2′-deoxyuridine + 2-oxoglutarate + O2 = uracil + 2-deoxyribonolactone + succinate + CO2
Other name(s): deoxyuridine-uridine 1′-dioxygenase
Systematic name: 2′-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (1′-hydroxylating)
Comments: Requires Fe(II) and ascorbate. cf. EC 1.14.11.3, pyrimidine-deoxynucleoside 2′-dioxygenase.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 98865-52-2
References:
1.  Stubbe, J. Identification of two α-ketoglutarate-dependent dioxygenases in extracts of Rhodotorula glutinis catalyzing deoxyuridine hydroxylation. J. Biol. Chem. 260 (1985) 9972–9975. [PMID: 4040518]
[EC 1.14.11.10 created 1989, modified 2002]
 
 


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