The Enzyme Database

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Accepted name: protocatechuate 4,5-dioxygenase
Reaction: protocatechuate + O2 = 4-carboxy-2-hydroxymuconate semialdehyde
For diagram of the protocatechuate 3,4-cleavage pathway, click here
Other name(s): protocatechuate 4,5-oxygenase; protocatechuic 4,5-dioxygenase; protocatechuic 4,5-oxygenase; protocatechuate:oxygen 4,5-oxidoreductase (decyclizing)
Systematic name: protocatechuate:oxygen 4,5-oxidoreductase (ring-opening)
Comments: Requires Fe2+.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, UM-BBD, CAS registry number: 9029-56-5
1.  Trippett, S., Dagley, S. and Stopher, D.A. The bacterial oxidation of nicotinic acid. Biochem. J. 76 (1960) 9.
[EC created 1965 as EC, transferred 1972 to EC]

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