| EC |
1.13.11.75 |
| Accepted name: |
all-trans-8′-apo-β-carotenal 15,15′-oxygenase |
| Reaction: |
all-trans-8′-apo-β-carotenal + O2 = all-trans-retinal + (2E,4E,6E)-2,6-dimethylocta-2,4,6-trienedial
|
|
For diagram of 8′-apo-β-carotenal metabolites, click here |
| Other name(s): |
Diox1; ACO; 8′-apo-β-carotenal 15,15′-oxygenase |
| Systematic name: |
all-trans-8′-apo-β-carotenal:oxygen 15,15′-oxidoreductase (bond-cleaving) |
| Comments: |
Contains an Fe2+-4His arrangement. The enzyme is involved in retinal biosynthesis in bacteria [2]. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Ruch, S., Beyer, P., Ernst, H. and Al-Babili, S. Retinal biosynthesis in Eubacteria: in vitro characterization of a novel carotenoid oxygenase from Synechocystis sp. PCC 6803. Mol. Microbiol. 55 (2005) 1015–1024. [DOI] [PMID: 15686550] |
| 2. |
Kloer, D.P., Ruch, S., Al-Babili, S., Beyer, P. and Schulz, G.E. The structure of a retinal-forming carotenoid oxygenase. Science 308 (2005) 267–269. [DOI] [PMID: 15821095] |
|
| [EC 1.13.11.75 created 2010 as EC 1.14.99.41, transferred 2013 to EC 1.13.11.75] |
| |
|
| |
|
Printable version