The Enzyme Database

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EC 1.13.11.70     
Accepted name: all-trans-10′-apo-β-carotenal 13,14-cleaving dioxygenase
Reaction: all-trans-10′-apo-β-carotenal + O2 = 13-apo-β-carotenone + (2E,4E,6E)-4-methylocta-2,4,6-trienedial
For diagram of 10′-apo-β-carotenal biosynthesis, click here
Other name(s): CCD8 (gene name); MAX4 (gene name); NCED8 (gene name); all-trans-10′-apo-β-carotenal:O2 oxidoreductase (13,14-cleaving)
Systematic name: all-trans-10′-apo-β-carotenal:oxygen oxidoreductase (13,14-cleaving)
Comments: Requires Fe2+. The enzyme from the plant Arabidopsis thaliana also catalyses EC 1.13.11.69, carlactone synthase, 10-fold faster.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Schwartz, S.H., Qin, X. and Loewen, M.C. The biochemical characterization of two carotenoid cleavage enzymes from Arabidopsis indicates that a carotenoid-derived compound inhibits lateral branching. J. Biol. Chem. 279 (2004) 46940–46945. [DOI] [PMID: 15342640]
[EC 1.13.11.70 created 2012]
 
 


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