The Enzyme Database

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EC 1.13.11.6     
Accepted name: 3-hydroxyanthranilate 3,4-dioxygenase
Reaction: 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde
For diagram of the later stages of tryptophan catabolism, click here
Other name(s): 3-hydroxyanthranilate oxygenase; 3-hydroxyanthranilic acid oxygenase; 3-hydroxyanthranilic oxygenase; 3-hydroxyanthranilic acid oxidase; 3HAO
Systematic name: 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)
Comments: Requires Fe2+.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, UM-BBD, CAS registry number: 9029-50-9
References:
1.  Decker, R.H., Kang, H.H., Leach, F.R. and Henderson, L.M. Purification and properties of 3-hydroxyanthranilic acid oxidase. J. Biol. Chem. 236 (1961) 3076–3082. [PMID: 13884755]
2.  Hayaishi, O. Direct oxygenation by O2, oxygenases. In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds), The Enzymes, 2nd edn, vol. 8, Academic Press, New York, 1963, pp. 353–371.
[EC 1.13.11.6 created 1965 as EC 1.13.1.6, transferred 1972 to EC 1.13.11.6]
 
 


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