A protein containing a selenocysteine residue. The products of action of EC 22.214.171.124 lipoxygenase on phospholipids can act as acceptors; H2O2 can also act, but much more slowly (cf. EC 126.96.36.199 glutathione peroxidase).
Ursini, F., Maiorino, M. and Gregolin, C. The selenoenzyme phospholipid hydroperoxide glutathione peroxidase. Biochim. Biophys. Acta839 (1985) 62–70. [DOI] [PMID: 3978121]
Schnurr, K., Belkner, J., Ursini, F., Schewe, T. and Kuhn, H. The selenoenzyme phospholipid hydroperoxide glutathione peroxidase controls the activity of the 15-lipoxygenase with complex substrates and preserves the specificity of the oxygenation products. J. Biol. Chem.271 (1996) 4653–4658. [DOI] [PMID: 8617728]