| EC |
1.1.99.24 |
| Accepted name: |
hydroxyacid-oxoacid transhydrogenase |
| Reaction: |
(S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate |
| Other name(s): |
transhydrogenase, hydroxy acid-oxo acid |
| Systematic name: |
(S)-3-hydroxybutanoate:2-oxoglutarate oxidoreductase |
| Comments: |
4-Hydroxybutanoate and (R)-2-hydroxyglutarate can also act as donors; 4-oxobutanoate can also act as acceptor. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 117698-31-4 |
| References: |
| 1. |
Kaufman, E.E., Nelson, T., Fales, H.M. and Levin, D.M. Isolation and characterization of a hydroxyacid-oxoacid transhydrogenase from rat kidney mitochondria. J. Biol. Chem. 263 (1988) 16872–16879. [PMID: 3182820] |
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| [EC 1.1.99.24 created 1992] |
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