| EC |
1.1.1.96 |
| Accepted name: |
diiodophenylpyruvate reductase |
| Reaction: |
3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD+ = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + NADH + H+ |
| Other name(s): |
aromatic α-keto acid; KAR; 2-oxo acid reductase |
| Systematic name: |
3-(3,5-diiodo-4-hydroxyphenyl)lactate:NAD+ oxidoreductase |
| Comments: |
Substrates contain an aromatic ring with a pyruvate side chain. The most active substrates are halogenated derivatives. Compounds with hydroxy or amino groups in the 3 or 5 position are inactive. |
| Links to other databases: |
BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 37250-31-0 |
| References: |
| 1. |
Zannoni, V.G. and Weber, W.W. Isolation and properties of aromatic α-keto acid reductase. J. Biol. Chem. 241 (1966) 1340–1344. [PMID: 5935348] |
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| [EC 1.1.1.96 created 1972] |
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