There are several forms of malate dehydrogenases that differ in their use of substrates and cofactors. This particular form is found only in the plant kingdom. Unlike EC 220.127.116.11, which catalyses a similar reaction, this enzyme can not bind oxaloacetate, and thus does not decarboxylate exogeneously-added oxaloacetate. cf. EC 18.104.22.168, malate dehydrogenase; EC 22.214.171.124, malate dehydrogenase (oxaloacetate-decarboxylating); and EC 126.96.36.199, D-malate dehydrogenase (decarboxylating).
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