The Enzyme Database

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EC 1.1.1.378     
Accepted name: L-rhamnose 1-dehydrogenase [NAD(P)+]
Reaction: L-rhamnose + NAD(P)+ = L-rhamnono-1,4-lactone + NAD(P)H + H+
Systematic name: L-rhamnose:NAD(P)+ 1-oxidoreductase
Comments: The enzyme, which occurs in the bacteria Azotobacter vinelandii and Sphingomonas sp. SKA58, is part of the non-phosphorylative degradation pathway for L-rhamnose. The enzyme differs in cofactor specificity from EC 1.1.1.173, L-rhamnose 1-dehydrogenase, which is specific for NAD+ and EC 1.1.1.377, L-rhamnose 1-dehydrogenase (NADP+).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Watanabe, S., Saimura, M. and Makino, K. Eukaryotic and bacterial gene clusters related to an alternative pathway of nonphosphorylated L-rhamnose metabolism. J. Biol. Chem. 283 (2008) 20372–20382. [PMID: 18505728]
2.  Watanabe, S. and Makino, K. Novel modified version of nonphosphorylated sugar metabolism – an alternative L-rhamnose pathway of Sphingomonas sp. FEBS J. 276 (2009) 1554–1567. [PMID: 19187228]
[EC 1.1.1.378 created 2014]
 
 


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