The enzyme participates in an alternative pathway for biosynthesis of (R)-pantothenate (vitamin B5). This entry covers enzymes whose stereo specificity for NADP+ is not known. cf. EC 126.96.36.199 2-dehydropantolactone reductase (Re-specific) and EC 188.8.131.52, 2-dehydropantolactone reductase (Si-specific).
Hata, H., Shimizu, S., Hattori, S. and Yamada, H. Ketopantoyl-lactone reductase from Candida parapsilosis: purification and characterization as a conjugated polyketone reductase. Biochim. Biophys. Acta990 (1989) 175–181. [DOI] [PMID: 2644973]