| EC |
1.1.1.338 |
| Accepted name: |
(2R)-3-sulfolactate dehydrogenase (NADP+) |
| Reaction: |
(2R)-3-sulfolactate + NADP+ = 3-sulfopyruvate + NADPH + H+ |
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For diagram of coenzyme-M biosynthesis, click here |
| Other name(s): |
(R)-sulfolactate:NADP+ oxidoreductase; L-sulfolactate dehydrogenase; (R)-sulfolactate dehydrogenase; ComC |
| Systematic name: |
(2R)-3-sulfolactate:NADP+ oxidoreductase |
| Comments: |
The enzyme from the bacterium Chromohalobacter salexigens can only utilize NADP+. It functions both biosynthetically in coenzyme M biosynthesis and degradatively, in the degradation of sulfolactate. It can not use (S)-malate and (S)-lactate. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 81210-65-3 |
| References: |
| 1. |
Denger, K. and Cook, A.M. Racemase activity effected by two dehydrogenases in sulfolactate degradation by Chromohalobacter salexigens: purification of (S)-sulfolactate dehydrogenase. Microbiology 156 (2010) 967–974. [DOI] [PMID: 20007648] |
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| [EC 1.1.1.338 created 2012] |
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