| EC |
1.1.1.336 |
| Accepted name: |
UDP-N-acetyl-D-mannosamine dehydrogenase |
| Reaction: |
UDP-N-acetyl-α-D-mannosamine + 2 NAD+ + H2O = UDP-N-acetyl-α-D-mannosaminuronate + 2 NADH + 2 H+ |
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For diagram of UDP-N-acetylgalactosamine and UDP-N-acetylmannosamine biosynthesis, click here |
| Other name(s): |
UDP-ManNAc 6-dehydrogenase; wecC (gene name) |
| Systematic name: |
UDP-N-acetyl-α-D-mannosamine:NAD+ 6-oxidoreductase |
| Comments: |
Part of the pathway for acetamido sugar biosynthesis in bacteria and archaea. The enzyme has no activity with NADP+. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Namboori, S.C. and Graham, D.E. Acetamido sugar biosynthesis in the Euryarchaea. J. Bacteriol. 190 (2008) 2987–2996. [DOI] [PMID: 18263721] |
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| [EC 1.1.1.336 created 2012] |
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