| EC |
1.1.1.30 |
| Accepted name: |
3-hydroxybutyrate dehydrogenase |
| Reaction: |
(R)-3-hydroxybutanoate + NAD+ = acetoacetate + NADH + H+ |
| Other name(s): |
NAD-β-hydroxybutyrate dehydrogenase; hydroxybutyrate oxidoreductase; β-hydroxybutyrate dehydrogenase; D-β-hydroxybutyrate dehydrogenase; D-3-hydroxybutyrate dehydrogenase; D-(-)-3-hydroxybutyrate dehydrogenase; β-hydroxybutyric acid dehydrogenase; 3-D-hydroxybutyrate dehydrogenase; β-hydroxybutyric dehydrogenase |
| Systematic name: |
(R)-3-hydroxybutanoate:NAD+ oxidoreductase |
| Comments: |
Also oxidizes other 3-hydroxymonocarboxylic acids. |
| Links to other databases: |
BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9028-38-0 |
| References: |
| 1. |
Bergmeyer, H.-U., Gawehn, K., Klotzsch, H., Krebs, H.A. and Williamson, D.H. Purification and properties of crystalline 3-hydroxybutyrate dehydrogenase from Rhodopseudomonas spheroides. Biochem. J. 102 (1967) 423–431. [PMID: 4291491] |
| 2. |
Delafield, F.P., Cooksey, K.E. and Doudoroff, M. β-Hydroxybutyric dehydrogenase and dimer hydrolase of Pseudomonas lemoignei. J. Biol. Chem. 240 (1965) 4023–4028. [PMID: 4954074] |
| 3. |
Lehninger, A.L., Sudduth, H.C. and Wise, J.B. D-β-Hydroxybutyric dehydrogenase of mitochondria. J. Biol. Chem. 235 (1960) 2450–2455. [PMID: 14415394] |
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| [EC 1.1.1.30 created 1961] |
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