EC |
1.1.1.288 |
Accepted name: |
xanthoxin dehydrogenase |
Reaction: |
xanthoxin + NAD+ = abscisic aldehyde + NADH + H+ |
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For diagram of abscisic-acid biosynthesis, click here and for carotenoid-epoxide rearrangements, click here |
Other name(s): |
xanthoxin oxidase; ABA2 |
Systematic name: |
xanthoxin:NAD+ oxidoreductase |
Comments: |
Requires a molybdenum cofactor for activity. NADP+ cannot replace NAD+ and short-chain alcohols such as ethanol, isopropanol, butanol and cyclohexanol cannot replace xanthoxin as substrate [3]. Involved in the abscisic-acid biosynthesis pathway in plants, along with EC 1.2.3.14 (abscisic-aldehyde oxidase), EC 1.13.11.51 (9-cis-epoxycarotenoid dioxygenase) and EC 1.14.13.93 [(+)-abscisic acid 8′-hydroxylase]. Abscisic acid is a sesquiterpenoid plant hormone that is involved in the control of a wide range of essential physiological processes, including seed development, germination and responses to stress [3]. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 129204-37-1 |
References: |
1. |
Sindhu, R.K. and Walton, D.C. Xanthoxin metabolism in cell-free preparations from wild type and wilty mutants of tomato. Plant Physiol. 88 (1988) 178–182. [PMID: 16666262] |
2. |
Schwartz, S.H., Leon-Kloosterziel, K.M., Koornneef, M. and Zeevaart, J.A. Biochemical characterization of the aba2 and aba3 mutants in Arabidopsis thaliana. Plant Physiol. 114 (1997) 161–166. [PMID: 9159947] |
3. |
González-Guzmán, M., Apostolova, N., Bellés, J.M., Barrero, J.M., Piqueras, P., Ponce, M.R., Micol, J.L., Serrano, R. and Rodríguez, P.L. The short-chain alcohol dehydrogenase ABA2 catalyzes the conversion of xanthoxin to abscisic aldehyde. Plant Cell 14 (2002) 1833–1846. [DOI] [PMID: 12172025] |
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[EC 1.1.1.288 created 2005] |
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