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Your query returned 1 entry. Printable version
EC | 1.1.1.282 | ||||
Accepted name: | quinate/shikimate dehydrogenase [NAD(P)+] | ||||
Reaction: | (1) L-quinate + NAD(P)+ = 3-dehydroquinate + NAD(P)H + H+ (2) shikimate + NAD(P)+ = 3-dehydroshikimate + NAD(P)H + H+ |
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For diagram of shikimate and chorismate biosynthesis, click here | |||||
Glossary: | quinate = (1R,3R,4R,5R)-1,3,4,5-tetrahydroxycyclohexanecarboxylic acid and is a cyclitol carboxylate The numbering system used for the 3-dehydroquinate is that of the recommendations on cyclitols, sections I-8 and I-9: and is shown in the reaction diagram. The use of the term '5-dehydroquinate' for this compound is based on an earlier system of numbering. |
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Other name(s): | YdiB; quinate/shikimate dehydrogenase (ambiguous) | ||||
Systematic name: | L-quinate:NAD(P)+ 3-oxidoreductase | ||||
Comments: | This is the second shikimate dehydrogenase enzyme found in Escherichia coli. It can use both quinate and shikimate as substrates and either NAD+ or NADP+ as acceptor. The low catalytic efficiency with both quinate and shikimate suggests that neither may be the physiological substrate. cf. EC 1.1.1.24, quinate/shikimate dehydrogenase (NAD+), EC 1.1.5.8, quinate/shikimate dehydrogenase (quinone), and EC 1.1.1.25, shikimate dehydrogenase (NADP+). | ||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||
References: |
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