Also acts on ethyl (R)-3-oxobutanoate and some other (R)-3-hydroxy acid esters. The (R)- symbol is allotted on the assumption that no substituents change the order of priority from O-3 > C-2 > C-4. A subunit of yeast fatty acid synthase EC 220.127.116.11, fatty-acyl-CoA synthase system. cf. EC 18.104.22.1680, (S)-3-hydroxyacid ester dehydrogenase.
Heidlas, J., Engel, K.-H. and Tressl, R. Purification and characterization of two oxidoreductases involved in the enantioselective reduction of 3-oxo, 4-oxo and 5-oxo esters in baker's yeast. Eur. J. Biochem.172 (1988) 633–639. [DOI] [PMID: 3280313]
[EC 22.214.171.1249 created 1990 as EC 126.96.36.199, transferred 2003 to EC 188.8.131.529, modified 2018]