The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

EC 1.1.1.279     
Accepted name: (R)-3-hydroxyacid-ester dehydrogenase
Reaction: ethyl (R)-3-hydroxyhexanoate + NADP+ = ethyl 3-oxohexanoate + NADPH + H+
Other name(s): 3-oxo ester (R)-reductase
Systematic name: ethyl-(R)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase
Comments: Also acts on ethyl (R)-3-oxobutanoate and some other (R)-3-hydroxy acid esters. The (R)- symbol is allotted on the assumption that no substituents change the order of priority from O-3 > C-2 > C-4. A subunit of yeast fatty acid synthase EC 2.3.1.86 fatty-acyl-CoA synthase). cf. EC 1.1.1.280 (S)-3-hydroxyacid ester dehydrogenase.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 114705-02-1
References:
1.  Heidlas, J., Engel, K.-H. and Tressl, R. Purification and characterization of two oxidoreductases involved in the enantioselective reduction of 3-oxo, 4-oxo and 5-oxo esters in baker's yeast. Eur. J. Biochem. 172 (1988) 633–639. [PMID: 3280313]
[EC 1.1.1.279 created 1990 as EC 1.2.1.55, transferred 2003 to EC 1.1.1.279]
 
 


Data © 2001–2016 IUBMB
Web site © 2005–2016 Andrew McDonald